Enhanced TLR2 responses in multiple sclerosis

Mechanisms Patients through TLR2-Dependent Responses in Cells from Multiple Sclerosis Helminth Antigens Modulate Immune

TLR2 – an innate immune checkpoint in multiple sclerosis

Our appreciation of the role of the innate immune system in the organ-specific autoimmunity is growing in parallel with better understanding of innate immunity and its function. Historically, more research had been devoted to adaptive immunity in initiating tissue damage in organ-specific autoimmune diseases, such as multiple sclerosis (MS). MS is an inflammatory demyelinating disease of the ce...

Multiple Sclerosis in Iran

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system (CNS). This highlydisabling disorder is characterized by a variable clinical course. MS is a heterogeneous disease with acomplex pathology and significant social and economic impact. MS is associated with dysfunction ofparts of the nervous system which results in a range of signs and symptoms, ...

Autonomic dysfunction (sweating responses) in multiple sclerosis.

Bladder disturbances and sexual impotence are common and distressing disorders occurring in multiple sclerosis. Miller, Simpson, and Yeates (1965) found bladder complaints occurring at some time of the disease in 78% of 297 patients, and in 52% of them it had persisted for over six months, while sexual impotence due to physical disease occurred in 44% of their patients. Although these disturban...

Immunotherapy in Multiple Sclerosis (Ms)

Summary The immunosuppressive agent has changed the clinical course of MS. Mostly,this agent, like cyclophosphamide cyclosporine A., and X-Ray of the lymphoid organ, has a lot of side effects. It should only be used in the most severe from of MS among immunosuppressive agents, Azathioprin has been used most frequently in spite of the fact that it is not very effective compared with other immun...